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PREGABALIN — 150 mg / 300 mg capsules

Gabapentinoid • neuropathic pain • fibromyalgia • epilepsy • anxiety (off‑label/approved) • Rx-only
Prescription-only medicine. Educational content: strengths, brand examples, safety notes, FAQ, and official references. Always follow your local leaflet and clinician guidance.

⚠️
Risk of dependence, abuse, and life‑threatening withdrawal
Controlled substance in US (Schedule V) and UK (Class C). Taper gradually — do not stop abruptly.
✅ Rx-only
✅ 150/300 mg
✅ Controlled in US/UK

🔎 Quick Links
📦 Snapshot
🧠 Overview
🏷️ Brands
⚠️ Safety
❓ FAQ
📚 References

📦 Product Snapshot

Active substancePregabalin
Strengths150 mg · 300 mg (also 25, 50, 75, 100, 200, 225 mg)
Dosage formCapsules · oral solution · prolonged‑release tablets (some markets)
150 mg and 300 mg are common maintenance doses. Available as immediate‑release capsules worldwide.
Reference brandLyrica® (Pfizer)
India brand examplesPregabid® · Pregalin® · Pregaba® · Maxgalin® · Pregamac®
Primary indicationsNeuropathic pain (diabetic, postherpetic, spinal cord injury) · Fibromyalgia · Epilepsy (adjunctive) · Generalized anxiety disorder (approved in EU/India, off‑label in US)
Label‑first: indications vary by country. GAD is approved in Europe and India but not FDA‑labeled for anxiety.

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Use our inquiry form to request official leaflet links, verify common strengths, and ask general authenticity/packaging questions. We do not provide medical advice.

International visitors: our informational support and inquiry form are available to users in the United States, United Kingdom, and Australia.


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Rx-only • label-first • verify local guidance

🧠 Overview

Pregabalin is a gabapentinoid that binds to the alpha‑2‑delta subunit of voltage‑gated calcium channels in the central nervous system. This binding reduces calcium influx at nerve terminals, decreasing the release of excitatory neurotransmitters such as glutamate, norepinephrine, and substance P. The result is a reduction in neuronal hyperexcitability, which underlies its efficacy in neuropathic pain, seizures, and anxiety.

Approved indications by region: In the US, pregabalin is FDA‑approved for neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, spinal cord injury, fibromyalgia, and as adjunctive therapy for partial‑onset seizures. In the European Union and India, it is also approved for generalized anxiety disorder (GAD) — a distinction that matters when reading local labels. Off‑label uses include other anxiety disorders, insomnia, and pruritus.

Dosing context for 150 mg and 300 mg: These strengths represent typical maintenance doses. Therapy is usually initiated at 75 mg twice daily or 150 mg once daily, titrated based on response and tolerability. The maximum recommended dose is 600 mg/day (in divided doses). Dosing is adjusted in renal impairment (creatinine clearance <60 mL/min) because pregabalin is eliminated renally unchanged.

Regulatory status: Pregabalin is a controlled substance in several countries due to emerging concerns about abuse, dependence, and withdrawal. In the US, it is Schedule V (lowest potential for abuse among controlled substances). In the UK, it was reclassified as a Class C controlled substance in 2019 following reports of misuse and overdose deaths. Prescriptions must reflect these local restrictions.

🏷️ Strengths & Brand Examples

Available strengths (globally)
  • 25 mg, 50 mg, 75 mg, 100 mg, 150 mg, 200 mg, 225 mg, 300 mg capsules
  • 20 mg/mL oral solution (for patients who cannot swallow capsules)
  • Prolonged‑release tablets (165 mg, 330 mg — some markets, for once‑daily dosing)
India brands (examples — 150 mg / 300 mg)
  • Pregabid® 150 / 300 (Sun Pharma)
  • Nervigesic 150 / 300 (Signature)
  • Nervismart 150 / 300 (Healing Pharma)
  • Pregarica 150 / 300 (Healing Pharma)
  • Prebasun 150 / 300 (Sunrise Remedies)
  • Pregalin® 150 / 300 (Cipla) — one of the most widely prescribed
  • Pregaba® 150 / 300 (Intas)
  • Maxgalin® 150 / 300 (Torrent)
  • Pregamac® 150 / 300 (Macleods)
  • Gabatin® 150 / 300 (Alkem)
Combination brands (India)
  • Pregabid-M® / Pregalin-M® (with methylcobalamin — for neuropathic pain with B12 deficiency)
  • Pregabid-NT® (with nortriptyline — for neuropathic pain)
Note: brand availability changes. Verify manufacturer and on‑pack labeling for current listings. In India, pregabalin is not a controlled substance, but prescriptions are still required.

⚠️ Safety, Side Effects & Monitoring

Commonly discussed effects
  • Dizziness, somnolence (very common — up to 40%)
  • Dry mouth, constipation
  • Blurred vision, diplopia
  • Peripheral edema (dose‑dependent)
  • Weight gain
  • Euphoria (can contribute to abuse potential)
  • Impaired concentration, ataxia (especially in elderly)
  • Thrombocytopenia (rare, but reported)
Serious risks & label-first warnings
• Angioedema: Can occur with or without history. Discontinue immediately if swelling of face, tongue, or larynx.
• Hypersensitivity: Skin redness, blisters, urticaria — discontinue.
• Suicidal ideation: Monitor for worsening depression or suicidal thoughts (antiepileptic drug class warning).
• Respiratory depression: Risk increased with concomitant opioids or CNS depressants, especially in elderly or those with respiratory impairment.
• Dependence and withdrawal: Abrupt discontinuation can cause insomnia, nausea, anxiety, diarrhea, and seizures. Taper over at least 1 week.
• Abuse potential: Pregabalin is abused for its euphoric effects, often at supra‑therapeutic doses. Use with caution in patients with history of substance abuse.
• Cardiac concerns: Can cause PR interval prolongation — use caution with other drugs that prolong PR interval.
Renal dosing adjustment (150 mg / 300 mg context)
Pregabalin is eliminated renally. CrCl ≥60 mL/min: usual dose 150‑600 mg/day in 2‑3 divided doses.
CrCl 30‑60 mL/min: reduce dose by 50% (e.g., 150 mg/day).
CrCl 15‑30 mL/min: reduce dose by 75% (e.g., 75 mg/day).
CrCl <15 mL/min: reduce proportionally (e.g., 25‑50 mg once daily).
Hemodialysis: supplemental dose after each 4‑hour session.

❓ FAQ

FAQ question #1: Is pregabalin the same as gabapentin?
Answer: They are related but not identical. Both are gabapentinoids, binding to the same calcium channel subunit. Pregabalin has higher potency, better bioavailability (>90% vs 30-60%), and linear pharmacokinetics, meaning dose increases produce predictable blood level increases. Clinically, pregabalin is often dosed twice daily while gabapentin requires three times daily due to shorter half-life.
FAQ question #2: Can I drink alcohol while taking pregabalin?
Answer: No, avoid alcohol. Both are CNS depressants and can cause additive sedation, dizziness, and respiratory depression. The combination also increases the risk of accidental overdose.
FAQ question #3: Is pregabalin addictive? Will I have withdrawal symptoms?
Answer: Yes, pregabalin has recognized abuse potential (especially in individuals with history of substance abuse) and can cause physical dependence. Withdrawal symptoms (insomnia, anxiety, diarrhea, confusion) occur if stopped abruptly. Always taper under medical supervision — do not discontinue suddenly.
FAQ question #4: Why is 150 mg or 300 mg prescribed only once or twice daily?
Answer: Pregabalin has a half-life of about 6 hours, but its pharmacodynamic effect lasts longer. Dosing is typically 2-3 times daily. 150 mg twice daily gives total 300 mg/day; 300 mg twice daily gives 600 mg/day (maximum). Some patients may tolerate once-daily dosing with extended-release formulations where available.
FAQ question #5: Does pregabalin cause weight gain?
Answer: Yes, weight gain is a known side effect, occurring in about 5-10% of patients. It is dose-dependent and may be due to increased appetite and fluid retention (peripheral edema). Monitor weight regularly, especially if diabetic or on other weight‑promoting medications.

⚠️ Medical disclaimer
Educational content only. This does not replace medical advice, diagnosis, or treatment. Prescription-only medicines should be used under clinician supervision and according to local approved labeling. Pregabalin may be a controlled substance in your country; follow local regulations.
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Pregabalin (Generic Lyrica) 150mg or 75mg
Average rating:  
 7 reviews
 by Matt, AU

The package arrived today. That was quick. Thank you!

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OXLEY VALE NSW
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 by Jason, USA

The last package arrived a couple days after our email. Perfect timing.

Thank you!

Jason

 by M. Hill, UK

Received 20 days after payment, better than expected. Thank you

 by Debra nielson

Thanks. This is the best generic lyrica I've used.

 by Neville, US

Thank you for your excellent service.

 by Jason, G

Your package arrived in record time today! Thank you very much!

2020-01-10 11:20ELKTON, MD 21921, Arrived at Post Office -> Your item arrived at the Post Office at 11:20 am on January 10, 2020 in ELKTON, MD 21921.
2020-01-10 07:59LINTHICUM HEIGHTS MD DISTRIBUTION CENTER, Departed USPS Regional Facility
2020-01-10 07:54LINTHICUM HEIGHTS MD DISTRIBUTION CENTER, Arrived at USPS Regional Facility
2020-01-09 13:03Inbound Out of Customs
2020-01-07 10:17Inbound Into Customs
2020-01-07 10:17ISC NEW YORK NY(USPS), Processed Through Facility
2020-01-04 18:19Origin Post is Preparing Shipment
2020-01-04 18:19INDIA, MUMBAI PARCELS, Processed Through Facility
2020-01-04 18:16INDIA, MUMBAI PARCELS, Processed Through Facility
2020-01-04 16:51INDIA, Acceptance

 by Terry daws

have the same effect most get from a few double gin and tonics, without the hangover, very good for anxiety, alongside mild benzo, doctors reluctant to prescribe as homeless and alcoholics seem to like the effects depriving millions of anxiety sufferers of a magical pil that actually works